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Senior Staff Engineer, Modeling

Industry-leading, global pharmaceutical company dedicated to putting patients at the center of everything through leading innovation in medicine.
$137,000 - $215,270
Data
Staff Software Engineer
In-Person
5,000+ Employees
3+ years of experience
Healthcare · Biotech

Description For Senior Staff Engineer, Modeling

Takeda's Synthetic Molecule Process Development (SMPD) team is seeking a Senior Staff Engineer specializing in Crystallization & Particle Engineering (Modeling). This role combines advanced engineering expertise with pharmaceutical development, focusing on developing robust, cost-effective processes for new small-molecule pharmaceuticals. The position requires expertise in crystallization kinetics, mass/heat transfer, and mathematical modeling, with a strong emphasis on population balance modeling (PBM).

The role involves leading challenging projects in particle engineering, establishing scale-up models, and applying process analytical technologies (PAT) combined with mathematical models. The successful candidate will work at the intersection of chemical engineering, data science, and pharmaceutical development, using both first-principle and data-driven approaches to optimize crystallization processes.

Working at Takeda means joining a global pharmaceutical leader committed to patient-centered innovation. The company offers comprehensive benefits including medical, dental, and vision insurance, 401(k) with company match, and generous paid time off. The position is based in Boston, MA, offering an opportunity to work with cutting-edge technology and contribute to developing life-changing medications.

This role is perfect for someone who combines deep technical expertise in crystallization modeling with strong leadership abilities and a passion for advancing pharmaceutical process development through computational approaches. The position offers significant opportunity for growth and impact in a collaborative, innovation-focused environment.

Last updated a month ago

Responsibilities For Senior Staff Engineer, Modeling

  • Lead crystallization process development using advanced modeling and simulation
  • Develop and validate predictive crystallization models
  • Design and execute experimental workflows with PAT integration
  • Develop digital twins for crystallization processes
  • Drive adoption of in-silico first approach
  • Provide technical leadership in crystallization modeling
  • Review and communicate modeling outcomes
  • Author technical reports and regulatory filings
  • Stay current with emerging trends in crystallization modeling
  • Champion knowledge-sharing and training across the organization

Requirements For Senior Staff Engineer, Modeling

Python
  • Ph.D. or postdoctoral fellowship in Chemical Engineering or related pharmaceutical science with 3+ years of relevant industry experience
  • Strong knowledge of crystallization, filtration, drying processes
  • Strong knowledge of transport phenomena and thermodynamics
  • Experience with crystallization and particle engineering modeling software
  • Experience with CFD modeling software
  • Proficient in communicating and data collection from systems
  • Experience with Matlab, Python, R, SQL, and good coding practices
  • Strong analytical and problem-solving skills
  • Excellent communication and technical writing skills
  • Good time management and organizational skills

Benefits For Senior Staff Engineer, Modeling

Medical Insurance
Dental Insurance
Vision Insurance
401k
Education Budget
  • Medical, dental, and vision insurance
  • 401(k) plan with company match
  • Short-term and long-term disability coverage
  • Basic life insurance
  • Tuition reimbursement program
  • Paid volunteer time off
  • Company holidays
  • Well-being benefits
  • 80 hours of sick time
  • 120 hours of paid vacation for new hires

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