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Senior Staff Engineer, Modeling

A global pharmaceutical company focused on R&D and delivering transformative therapies to patients, with operations in over 70 countries.
$137,000 - $215,270
Data
Staff Software Engineer
In-Person
5,000+ Employees
3+ years of experience
Healthcare · Biotech

Description For Senior Staff Engineer, Modeling

Takeda, a leading global pharmaceutical company with over 230 years of history, is seeking a Senior Staff Engineer specializing in Modeling to join their Synthetic Molecule Process Development (SMPD) team. This role sits within the Process Engineering & Technology Group, where you'll be at the forefront of developing robust and cost-effective processes for manufacturing new small molecule pharmaceuticals.

The position requires a strong background in chemical reaction engineering and will involve leading challenging problems in chemical reactions by leveraging expertise in reaction kinetics, transport phenomena, mathematical modeling, and reactor design. You'll be responsible for developing scale-up and scale-down models for studying unit operations using both first-principle and data-based models.

As a Senior Staff Engineer, you'll work with cutting-edge process analytical technologies (PAT) combined with mathematical models to enhance process understanding and enable effective development, optimization, and scale-up of processes using in-silico approaches. The role offers an opportunity to work with advanced modeling tools and digital twin functionalities, implementing model-based design of experiments for process characterization and risk assessment.

The position offers a competitive salary range of $137,000 to $215,270, along with comprehensive benefits including medical, dental, and vision insurance, 401(k) with company match, disability coverage, and generous paid time off. You'll be part of a global organization that values innovation, collaboration, and patient-focused outcomes.

This role requires approximately 5-10% travel and offers the opportunity to work with cross-functional teams across the globe. You'll be based in Boston, MA, working alongside world-class R&D professionals who are pushing the boundaries of what's possible in pharmaceutical development. The position represents an excellent opportunity for someone looking to make a significant impact in pharmaceutical process development while working for a company that consistently ranks as a Global Top Employer.

Last updated 3 days ago

Responsibilities For Senior Staff Engineer, Modeling

  • Lead process modeling and simulation for drug substance manufacturing
  • Develop and implement digital twins of unit operations
  • Design and develop experimental workflows for model development
  • Partner with cross-functional teams to develop M&S solutions
  • Implement in-silico tools for process development
  • Contribute to democratization of modeling and simulation tools
  • Review and communicate data across pharmaceutical sciences teams
  • Author regulatory documents and peer-reviewed manuscripts
  • Manage vendor relationships and technology partnerships

Requirements For Senior Staff Engineer, Modeling

Python
  • PhD or postdoctoral fellowship in Chemical Engineering with 3+ years industry experience
  • Strong knowledge of chemical reaction engineering and catalysis
  • Strong knowledge of transport phenomena and thermodynamics
  • Experience with reaction kinetic modeling software (Ansys, ReactionLab, Dynochem, gPROMS)
  • Experience with CFD modeling software (Ansys, Star CCM+, MStar CFD)
  • Proficient in communicating and data collection from systems
  • Experience with Matlab, Python, R, SQL, and good coding practices

Benefits For Senior Staff Engineer, Modeling

Medical Insurance
Dental Insurance
Vision Insurance
401k
Education Budget
  • Medical, dental, and vision insurance
  • 401(k) plan with company match
  • Short-term and long-term disability coverage
  • Basic life insurance
  • Tuition reimbursement program
  • Paid volunteer time off
  • Company holidays
  • 80 hours of sick time
  • 120 hours of paid vacation for new hires
  • Well-being benefits

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